LTF and osteoporosis: Lactoferrin is an endogenous multifunctional iron-binding glycoprotein with a variety of biological functions such as immunomodulation, metabolic regulation, bone homeostasis regulation, antiviral, antihypertension (4), attenuation of cardiac remodeling and improvement of cardiac function, which has potential therapeutic value for a variety of diseases, such as osteoporosis, osteoarthritis, bone fracture, obesity, hypertension, and Alzheimer’s (5).