The proposed follow-up for this patient includes annual screening for autoimmune thyroid disease (thyroid-stimulating hormone [TSH], free thyroxine [fT4], anti-thyroid peroxidase [TPO] antibodies, anti-thyroglobulin [TG] antibodies, as well as anti-TSH receptor antibodies [TRAb]) and yearly clinical evaluation for Addison’s disease, with targeted hormonal and antibody testing in case of clinical suspicion. The gene discussed is TG; the disease is primary adrenal insufficiency.