Neutrophils recruited in IRI-AKI are characterized by lower levels of CD11b, CD54, and CD95, whereas neutrophils in CLP-induced SA-AKI predominantly exhibit a CD11bhigh, CD54high, and CD95high phenotype, indicating enhanced phagocytic capacity, ROS generation, rolling, and adhesion functions in the latter19. The gene discussed is ICAM1; the disease is acute kidney injury.