Malnutrition was a strong predictor (adjusted OR: 2.41; 95% CI: 1.82–3.22; P < 0.001), along with BMI <18.5 kg/m2, anemia, elevated preoperative CRP, advanced FIGO stage, ovarian cancer, open surgery, preoperative lymphopenia, and age ≥60 years (all P < 0.05). The gene discussed is CRP; the disease is ovarian carcinoma.