RACK1 and Alzheimer disease: In the probe trial, compared with mice in the Rack1 WT/AD group, Rack1 cKO/AD mice demonstrated reduced latency to find the platform (Figure 2C), along with increases in the time spent in the target quarter (Figure 2D) and number of times crossing the platform location (Figure 2E); however, swimming speed was unchanged (Figure 2F,G).