Notably, antibodies like 23C6, potentially targeting the αvβ3 activation state,[46, 47] and αvβ3 inhibitors such as peptides cyclo(─RGDfK) and cilengitide, significantly interfere with the mutually stable coexistence of αvβ3 and CD47 on cancer cell surfaces (Figure 4; Figure S10, Supporting Information). This evidence concerns the gene CD47 and cancer.