In this study, we found a pronounced correlation between CD47 and αvβ3 expression in clinical samples of 119 breast cancer tissues and nine cancer cell lines, particularly the triple‐negative breast cancer (TNBC) cell lines MDA‐MB‐231.[40] Reducing the surface expression of either CD47 or αvβ3 on tumor cells substantially lowered the distribution of the other on the membrane. This evidence concerns the gene CD47 and cancer.