ITGAM and neoplasm: Notably, PSFL‐NK13 treatment also promoted macrophage infiltration of HCT116 tumor tissue and enhanced macrophage phagocytosis, as indicated by increased CD11b expression (control vs 2 mg kg−1 PSFL‐NK13, p = 0.0197, Student's t‐test; Figure S18B, Supporting Information), alongside an increase in macrophage infiltration in peripheral blood (31.2 ± 9.0% vs 45.0 ± 10.6%, p = 0.0347; Figure S18C, Supporting Information).