For example, we have recently found that lnc‐HZ09 suppresses PLD1/RAC1/CDC42 pathway and migration/invasion to induce women miscarriage;[38] lnc‐HZ10 suppresses homologous recombination repair to induce miscarriage;[48] and lnc‐HZ12 suppresses autophagy degradation of BBC3 to cause apoptosis and induces miscarriage.[40] In this study, lnc‐HZ05 suppresses trophoblast cell migrasome formation by disrupting TGFβ2 pathway and induces miscarriage. The gene discussed is RAC1; the disease is spontaneous abortion.