The amino acid sequences of TGFβ2, TGFβR2, Smad3, NDST1, and TSPAN4 were all conservative in both human and mouse (Table S8, Supporting Information); however, the analogue of lnc‐HZ05 was not identified in mouse.[34] Therefore, we selected recombinant Tgfβ2 protein, which has been widely used in various intervention or treatment in dermal papilla cells, ex vivo cultured human cornea model, lamprey model, or mouse model.[58, 59, 60, 61] Then, Tgfβ2 protein, with normal saline as control, was intraperitoneally injected into this mouse miscarriage model (Figure11A). Here, TSPAN4 is linked to spontaneous abortion.