TGFB2 and autoimmune disease: In addition to miscarriage treatment, TGFβ2 could also be used as detection indicator for various diseases, such as autoimmune diseases, cancer, fibrosis, and cardiovascular diseases.[70, 71] In this study, we also find that TGFβ2 protein levels in serum are significantly lower in RM versus HC groups and could be used as a detection indicator for prediction of miscarriage risk.