Coculture with SLAMF7-overexpressing CT26 tumor cells significantly increased CD107a (Lysosomal-associated membrane protein 1, LAMP1) surface expression on DNT, a maker of degranulation, compared to control CT26 cells, indicating that SLAMF7 ligation could promote DNT cell degranulation (Fig. 3B). Here, SLAMF7 is linked to neoplasm.