In cases of parent-newborn diseases, the mean expression of immune senescence markers (CD57+KLRG1+) on senescent T cells and natural killer cells was elevated (M:93.3%, F:74.2%, N:45.7%), while a decreased expression of markers was observed in healthy parent-newborn pairs (M:26.6%, F:42.5%, N:18.6%) (Fig. 2). Here, B3GAT1 is linked to glycogen storage disease VI.