Since it is inherently an age-associated disease, AMD prevalence is expected to double by 2040 due to aging populations (Wong et al, 2014), but other environmental and genetic variables such as smoking or the presence of the CFHY402H (complement factor H) polymorphism have also been linked to higher AMD incidence (Landowski et al, 2019). This evidence concerns the gene CFH and age-related macular degeneration.