For example, different isoforms of BRD4 explain why earlier studies reported the BRD4 reader protein as a tumour suppressor, while others described it as an oncogene (Crawford et al, 2008; Shi et al, 2014; Shu et al, 2016; Han et al, 2020; Wu et al, 2020). Here, BRD4 is linked to neoplasm.