TRPC6 and kidney disorder: Notwithstanding their implication in certain kidney diseases, it is likely that TRPC6 channels have normal physiological functions in podocytes, as they are components of rapidly acting GPCR pathways tied to Ca2+ influx in podocytes, including signals mediated by angiotensin II (Ilatovskaya et al., 2014), P2Y receptors (Roshanravan & Dryer, 2014), κ‐opiate receptors (Golosova et al., 2020), bioactive lipids (Roshanravan et al., 2016), and metabotropic glutamate receptors (Wang et al., 2019).