DES and Desminopathy: When looking for proteins that were reported to be enriched in fibres containing protein aggregates in skeletal muscle tissue from desminopathy patients (n = 19) [24] (Table S8, column S; Table S8, 2nd sheet, column S), Mlf2 (myeloid leukaemia factor 2) was up‐regulated on the protein level in both the heterozygous and homozygous R405W desmin knock‐in mice, and Psmb4, Xirp2 and Dcxr only in the homozygous phenotype.