IFT27 and Bardet-Biedl syndrome: In addition to identifying known structural components, our first study (Mick et al., 2015) performed proteomic profiling in a BBS model cell line, in which Ift27 (also known as Bbs19) was disrupted, and recapitulated the accumulation of the BBSome as well as GPCRs in the Ift27 mutant cilia (Eguether et al., 2014; Liew et al., 2014).