X-linked severe combined immunodeficiency (X-SCID), caused by mutations in the interleukin-2 receptor gamma chain (IL2RG) gene, is one of the most common forms of SCID, accounting for approximately 50%–60% of cases (Mahdavi et al., 2021). This evidence concerns the gene IL2RG and T-B+ severe combined immunodeficiency due to gamma chain deficiency.