CAFs, activated by tumor cells, promote tumor growth, progression, angiogenesis, and drug resistance by secreting cytokines like transforming growth factor‐β (TGF‐β), platelet‐derived growth factor (PDGF), vascular endothelial growth factor (VEGF), and interleukins (ILs) [8]. The gene discussed is TGFB1; the disease is neoplasm.