Meanwhile, the arthrosis appearance, H&E, micro‐CT, and safranine O and green staining also revealed the improvements in synovial inflammation and cartilage destruction in the IGF2BP3 KO arthritis mice compared with the WT arthritis mice (Figure S7A–C); while CEL did not show further relieved effects in IGF2BP3 KO arthritis mice. This evidence concerns the gene IGF2BP3 and Arthritis.