ERBB2 and neoplasm: In our previous study, we found that hydroxyethyl starch (HES)-coated bionized nanoferrite (BNF–starch) nanoparticle (BP), human epidermal growth factor receptor 2 (HER2+ve) tumor-targeting antibody-coated BP (BNF–starch–herceptin ((BH)), and a non-specific control antibody-coated BP, (BNF–starch–IgG (BIgG)) were taken up by stromal and immune cells in the tumor microenvironment (TME) after systemic injection (Healy et al., 2023).