Nelson M.P., Boutin M., Tse T.E., Lu H., Haley E.D., Ouyang X.,Zhang J., Auray-Blais C., Shacka J.J. The lysosomal enzyme alpha-Galactosidase A is deficient in Parkinson’s disease brain in associationwith the pathologic accumulation of alpha-synuclein. Here, SNCA is linked to Parkinson disease.