Association with COPD was established with FOXO1 (rs12585277) (Padj = 0.0018, OR = 1.44 for the AG genotype) and FOXO3A (rs2253310) (Padj = 5.926 × 10–7, OR = 1.99 for the GG genotype). The gene discussed is FOXO1; the disease is chronic obstructive pulmonary disease.