FOXO1 and chronic obstructive pulmonary disease: The frequencyof the A-G haplotype at rs12585277 and rs9549240loci of the FOXO1 gene was higher in the COPD group(24.29 vs. 18.81 % in controls, Padj = 0.022, OR = 1.3695 % CI 1.05–1.76) (Table S4).