A second in vitro study revealed that wogonin increased the expression of p53 and the Nrf2 signaling pathway and suppressed the glucose transporter 1 (GLUT1), NF‐κB, p‐I‐B, and p‐IKK in the CRC HCT‐116 cells. The gene discussed is NFKB1; the disease is colorectal carcinoma.