In the nucleus, SREBP1‐coordinated wogonin can inhibit the transcription of the oncogene by downregulating the YAP/TAZ transcriptional activity through the LATS1/MOB signaling pathway, respectively, decreasing the expression of the oncogenes and fatty acid synthase (FASN); the expression of the gene is important in the growth of the rapidly developing tumor cells. The gene discussed is YAP1; the disease is neoplasm.