For identification of adult pulmonary TB, regardless of HIV status, we identified an 8-marker signature consisting of FGF, IL-1β, IL-8, IL-10, IL-12p70, IL-13, MIP-1β and VEGF which gave an AUC of 0.78 (95% CI: 0.75, 0.84), sensitivity of 79% (95% CI: 75, 84) and specificity of 67% (95% CI: 60, 73) (Table 2). This evidence concerns the gene CXCL8 and pulmonary tuberculosis.