Antibodies associated with SPSD include anti-GAD65 antibodies usually found in classic SPS, anti-glycine receptor (anti-GlyR) antibodies commonly found in PERM, antibodies against amphiphysin/dipeptidyl-peptidase-like protein(DPPX) in subsets, including paraneoplastic, etc. H1N1 virus infection is associated with seizures, influenza-associated encephalopathy or encephalitis (IAE) (3), acute disseminated encephalomyelitis (ADEM), Guillain-Barre syndrome (4). Here, AMPH is linked to acute disseminated encephalomyelitis.