MCL1 and neoplasm: The study revealed that the presence of anti-apoptotic proteins B-cell lymphoma 2 (Bcl-2) and Myeloid Cell Leukemia 1 (Mcl-1) is markedly upregulated in the tumor tissue of CRLM patients and correlates with a reduction in mitochondrial membrane potential (ΔΨm) (86, 87).