Zhu et al. (150) reported that nude mice inoculated with EC9706 cells and administered 200 μL/d of FFKS intraperitoneally for 4 weeks exhibited reduced PCNA and Bcl-2 expression and a tumor inhibition rate of 49%, likely mediated by caspase-3 activation and Fas upregulation. The gene discussed is CASP3; the disease is neoplasm.