Biomarkers of liver fibrosis, such as FN, Collagen I, desmin, and α‐SMA, were detected, and 10 mg·kg−1 Ssb1 exerted a considerable effect on fibrosis alleviation; which had about the same efficacy as the commercial inhibitor S3I‐201 (Figure 9A; Figure S13C). The gene discussed is ACTA1; the disease is Hepatic fibrosis.