Collected data included patient demographics, incidence of shunt-related intracranial hemorrhage, antithrombotic use, preoperative international normalized ratio, platelet count (within 2 weeks preoperatively), postoperative CRP levels (on day 1), time to seizure onset, and previous intracranial hemorrhage, cerebral infarction, or neurosurgery. The gene discussed is CRP; the disease is brain infarction.