The analysis revealed that gender, UACR, 24hUpro, Hb, Alb, TC, HDL-C, IFTA, NONO expression, MMP-9 expression, Col-I expression, Col-III expression, and collagen volume percentage were all factors influencing the prognosis of DN patients (P<0.05) (Table 4). Here, MMP9 is linked to liver dysplastic nodule.