Although both Swyer syndrome and CAIS can present with PA and increased risk of gonadal tumors due to the presence of Y chromosome, cases with Swyer syndrome may complain of delayed puberty, different from that in CAIS, and have their own hormonal characteristics due to the dysfunctional gonads, including increased FSH and LH levels and decreased E, T, and AMH concentrations (71). The gene discussed is BRD2; the disease is complete androgen insensitivity syndrome.