Comprehensive genetic testing, including PRSS1 (serine protease 1, cationic trypsinogen), SPINK1 (serine peptidase inhibitor Kazal type 1), CFTR (cystic fibrosis transmembrane conductance regulator), and CTRC (chymotrypsin C), was negative, supporting the classification of AP as idiopathic. This evidence concerns the gene SPINK1 and alkaline phosphatase measurement.