SLAMF8 and posterior cortical atrophy: Our findings indicate that SLAMF8 is an independent prognostic factor for distant metastasis in PCa, as shown by in the TCGA cohort (HR = 1.063, P = 0.023) (Fig. 2F), GSE11691 cohort (HR = 1.682, P = 0.029) (Fig. 2G), and MSKCC cohort (HR = 2.412, P = 0.040) (Fig. 2H).