As expected, kidney transcript expression of genes linked to the partial EMT and fibrosis were elevated in DKD mice, as evidenced by increased renal mRNA expression of Col1a1 and Acta2 (smooth muscle alpha-actin), along with decreased Cdh2 (N-cadherin) and Cdh1 (E-cadherin) levels. The gene discussed is ACTA2; the disease is diabetic kidney disease.