This result conformed that CD24/Siglec-10 axis exerts the negative regulatory role in DAMP-induced inflammatory response, suggesting that the delayed decrease in serum sSiglec-10 levels was associated with the poor prognosis despite the presence of increased sCD24, which is similar to a previous study that a sustained elevation in Siglec-10 levels was related to a more favorable outcome in patients with intracranial hemorrhage from aneurysmal rupture22. This evidence concerns the gene CD24 and intracranial hemorrhage.