RPS3 and psoriasis: We identified PSMA6, a reported genetic risk factor for the development of psoriasis and IBD52,53, PSMA7 (proteasome 20S subunit alpha), a biomarker of IBD54, and RPS3 (ribosome small 40S subunit) as potential LZTR1-interacting proteins (Supplementary Fig. S14i), while only PSMA7 and RPS3 were validated through co-IP (Fig. 8g).