SREBF1 and diabetes mellitus: Quantitative PCR of livertissues (n=8/group) demonstrated that STZ-induced diabetes significantlyupregulated SREBP-1C mRNA expression (2.71±0.17-fold vs. normal controls,P<0.01, one-way ANOVA with Tukey’s test), which was attenuated by 63.16% inHM+STZ group (1.00±0.05 vs. STZ, P<0.05), suggesting suppression oflipogenesis (Fig. 4a).