Patients with meningococcal meningitis had a higher prevalence of anti-IFN-γ (9 of 86 [10%] vs. 3 of 264 [1%], p = 0.004), anti-IL-1α (6 of 86 [7%] vs. 1 of 264 [0%], p = 0.015), and anti-IL-17F (6 of 86 [7%] vs. 1 of 264 [0%], p = 0.015) compared to controls (Table 2). Here, IL1A is linked to meningococcal meningitis.