The expression level of OCN was significantly higher in the DRG2 KO‐OM group than the WT‐OM group on days 7 and 14 (day 7, p < 0.01; day 14, p < 0.01), and it was significantly higher in the DRG2 KO‐GM than the WT‐GM on day 7 (p < 0.05). The gene discussed is BGLAP; the disease is ocular melanoma.