Two partial responses occurred in patients with pancreatic cancer and ataxia telangiectasia mutated (ATM) alterations: 32% decrease in an ATM E11828/ATM K1109* tumor lasting 15.8 months and 57% decrease in an ATM R3008H/germline ATM R1882* tumor lasting 13.6 months. This evidence concerns the gene ATM and pancreatic neoplasm.