issue, the investigators monitored the effects of artesunate on CD4 + and CD8 + T cells, Treg and NK cells in transgenic tumor-bearing mice and non-transgenic mice, in addition to finding that artesunate inhibited melanoma cell growth and induced apoptosis, but that apoptosis of tumor cells was not attenuated with immunosuppression [106]. This evidence concerns the gene CD4 and neoplasm.