In the group of 10 patients with energy malnutrition (BMI <20.0 kg/m2), impaired appetite and the risk of further weight loss within the next 6 months (SNAQ ≤14) were diagnosed in six patients (60%), malnutrition (SGA ≤5) was observed in nine patients (90.0%) and protein malnutrition (albumin <3.5 g/dL) was present in one patient (10%). The gene discussed is ALB; the disease is malnutrition.