Interestingly, many of the DMGs identified had multiple roles and several were potential cancer biomarkers or were previously shown to be implicated in various types of cancers, including ABLIM1 [98], ADAM12 [99–101], ARHGEF4 [102], FBLN2 [103,104], ITGA6 [105,106], LRPAP1 [107], Ly9 [108], NT5E [109], PITPNC1 [110,111], PLCG1 [112–114], OBSCN [115,116], RHOH [117,118], SPTBN1 [119,120], SPOCK2 [121] and SPRY1 [122]. The gene discussed is SPRY1; the disease is cancer.