Further, lamin B1 and ‐A are not typically mutated in cancers, but sometimes differentially expressed, highlighting the relevance of controlled expression similar to endogenous levels.[54, 55, 56] While ectopic expression may not fully reflect endogenous lamin levels, our data indicate no interference with cell behavior or treatment sensitivity, making the system robust and informative. This evidence concerns the gene LMNB1 and cancer.