AGO2 and lung cancer: Given the lack of nucleus‐based machinery in RBCs, it is proposed that exosomes and Argonaute 2 (Ago2) function as primary transporters of molecules crucial for facilitating communication from RBCs to other cells.[21, 32] To further explore the mechanism through which RBC‐derived miR‐93‐5p is transferred to lung cancer cells, we collected RBCs from 10 lung cancer patients and 10 healthy controls, cultured them, and isolated exosomes (Figure 2D) and Ago2‐associated immunoprecipitation (IP) products from the RBC‐medium.