ACTA1 and neoplasm: Flow cytometry further revealed that TAMC‐conditioned media derived from AG‐stimulated tumor cell supernatants enhanced the iCAFs phenotype and attenuated its myCAFs phenotype in primary CAFs, as evidenced by a noticeable increase in the proportion of IL‐6+ CAFs (control: 5.52 ± 0.86%, AG: 16.85 ± 4.36%, FOLFIRINOX: 7.24 ± 2.48%) and a distinct decrease in the proportion of α‐SMA+ CAFs (control: 76.54 ± 2.54%, AG: 44.65 ± 4.99%, FOLFIRINOX: 68.61 ± 3.97%) (Figure 5C–F).