The growing understanding of the multifaceted roles of MIF in shaping the immunosuppressive microenvironment, malignant progression, and metastasis has stimulated the development of targeted approaches, ranging from small‐molecule inhibitors and monoclonal antibodies.[28, 29, 30] The results from four large multicenter cohorts indicated significant overexpression of MIF in PDAC tumor tissues (Figure S13G–J, Supporting Information). The gene discussed is MIF; the disease is neoplasm.