To further verify the activation of SAL1‐PAP retrograde signaling following ToCV infection or p22‐transgenic expression, we employed norflurazon (NF) treatment, which is known to suppress the expression of photosynthesis‐related nuclear genes via disrupting chloroplast retrograde signaling.[34] By applying NF, we successfully inhibited the retrograde signaling, as evidenced by the significantly reduced expression levels of NbLHCB2.1 and NbCA1 (Figure S2, Supporting Information). The gene discussed is SALL1; the disease is infection.