Typically, primary colorectal adenocarcinomas are CK7-negative and strongly express CK20, CDX2, and SATB2.15,16) In our case, the intestinal tumors were negative for CK7 and CK20, with absent to weak CDX2 expression, and only weak SATB2 staining. Here, SATB2 is linked to colorectal adenocarcinoma.