ALPL and osteogenesis imperfecta: Alleles T, C, and A of ALPL rs121918007 are associated with adult HPP; meanwhile, allele A is also related to childhood, infantile, and odontohypophosphatasia presentations, serum alkaline phosphatase levels, choline phosphate levels, osteogenesis imperfecta, and inborn genetic diseases [12,14-17].