An inverse expression correlation was observed between DUSP1 and Snail and activated MAPKs in prostate cancer tumors; high DUSP1 expression is associated with low activated JNK, ERK, and Snail levels, and the study further pointed out that the higher levels of DUSP1 expression exhibit better prognosis and extended survival in PCa patients.82 This evidence concerns the gene MAPK1 and Familial prostate cancer.