There were no significant differences in the levels of HDL-C, CHO, TG, FSH, LH, E2, T, Pro and PRL between the PCOS-NIR and PCOS-IR groups (P>0.05), as shown in Table 2 After treatment, there were no significant differences in body weight, BMI, waist circumference, hip circumference and WHR of the two groups than those of before treatment (P>0.05), as shown in Table 1. The gene discussed is PLOD1; the disease is polycystic ovary syndrome.