TNF and cystic fibrosis: Table 2 describes the pathways involved in each gene and is also described in Table S2. Only TNF and TGFB1 had intersecting pathways, whereby 26 pathways were described. The KEGG and REACTOME ID numbers are also reported in Table 2. Due to intersecting pathways, TNF, TGFB1 and the CFTR gene were also analysed to understand the pathways specifically in CF that may be impacted, as described in Figure 4.